I wouldn't worry yourself. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Medically reviewed by Drugs.com. Is it safe to take cough remedies containing phenylephrine while pregnant? You may report side effects to the FDA at 1-800-FDA-1088. Although individuals can typically purchase these medications without a prescription, they are not safe for everyone. Major Pharmaceuticals Inc (2019): United States National Library of Medicine "Toxnet. Contraindications feature history of a heart attack, adrenal glandular problem or thyrotoxicosis. are linked to rare birth defects of the digestive tract, ear and heart. Nighttime pills typically contain either phenylephrine or pseudoephedrine in addition to an antihistamine, a substance that causes drowsiness in most people. [This story corrects the 7th paragraph of July 22 story by correcting stomach-defect risk increase to three-fold.]. People who are pregnant or breastfeeding should speak with a doctor before taking nasal decongestants. Eventually, that reduces the conditions to allow for normal breathing. For these, please consult a doctor (virtually or in person). This medication comes in solution form and is injected into a vein by a healthcare professional during surgical procedures. Animal studies have not been conducted. The typical low-dose aspirin you can buy without a prescription is 81 mg. Low-dose aspirin is safe to use throughout pregnancy. Can you take phenylephrine and pseudoephedrine? Follow the directions on your prescription label carefully. Tell your doctor if you are breastfeeding or plan to breastfeed. Based Learn more. I am a bot, and this action was performed automatically. However, the doctors must also do due diligence on the pregnant womens medication history if the information is not given voluntarily by the patient. Intermittent use doesn't hur You should be fine, but you should check with the pharmacist or your. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. July 30, 2022. See here for a complete list of exchanges and delays. Sore throat, coughing, runny nose, sinus headachesugh! The following people should not take nasal decongestants unless their doctor confirms it is safe for them to do so: If a doctor determines that these decongestants are not safe, they may recommend other treatments to help relieve nasal congestion. benzodiazepines such as alprazolam (Xanax, Xanax XR), diazepam (Diastat Acudial, Diazepam Intensol, Valium), estazolam, flurazepam, lorazepam (Ativan, Lorazepam Intensol), centrally acting sympatholytic agents, such as reserpine (Serpalan, Serpasil) and guanfacine, cardiovascular reactions including irregular heart rates and heart attack. Last updated on May 19, 2022. If taking a home pregnancy test isn't possible, stop taking birth control pills until you can see a health care provider to find out if you're pregnant. i think you'll be okif u don't feel safe taking it then I wouldn't..try something like benedryl or tylonal pm. Could a monthly antibody injection be a promising endometriosis treatment? i was talking with my doc, and the REAL sudafed (the stuff behind the counter) is okay the sudafed stored on the shelves isn't but he didn't say why just cuz its over the counter doesn't mean its okay for us! Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. Animal studies are not available for the combination product. It also explores some potential side effects of these medications, as well as their possible interactions with other drugs. Medications can interact with certain foods. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Sore throat Throat lozenges containing local anaesthetic and antibacterial agents may be used in pregnancy. To provide you with the most relevant and helpful information, and understand which Keep this and all medicines out of the reach of children. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. Accessed July 15, 2022. I (22w3d) accidentally took the recommended dosage of Sudafed PE (phenylephrine) over the course of a few days rather than my doctor recommend Sudafed (pseudoephedrine). PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING PHENYLEPHRINE HYDROCHLORIDE OPHTHALMIC SOLUTION. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you feel bad don't take it again but other than that don't worry :). Saunders Elsevier; 2016. https://www.clinicalkey.com. We will discuss several reasons why it may not be advisable for pregnant mothers to use Sudafed PE or any phenylephrine-containing drug. Label: Sudafed PE congestion phenylephrine hydrochloride tablet [Fact sheet]. http://www.tga.gov.au/docs/html/medpreg.htm" (2010): "Product Information. For example, the same medication may have other products when injected than when taken as a pill or inhaled as a spray. I am sure everything is fine since you only took it one time. This should offer some reassurance to women who have taken these medications in pregnancy, Mitchell said. 1997-2023 BabyCenter, LLC, a Ziff Davis company. Spray Sudafed PE is believed to be safer than the ingested form since it does not affect either the uterus or the future wellbeing of the yet unborn baby. the unsubscribe link in the e-mail. All were associations that had been suggested by earlier studies. Temporarily relieves sinus pressure and congestion. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. WebDoes taking phenylephrine increase the chance of birth defects? Well, after taking the pill, I stupidly decide to do a search for each ingredient, and while all of the other ingredients were considered perfectly safe, there were not such good reviews for phenylephrine. First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. Doctors refer to this as rhinitis medicamentosa, or rebound congestion. NEW YORK (Reuters Health) - A womans use of decongestant medications in the first trimester of pregnancy may raise her childs risk of certain rare birth defects, according to a small study. Available for Android and iOS devices. Major birth defects of any kind affect about two to three percent of liveborn infants, so they are rare, study author Dr. Allen Mitchell said. What Pregnant People Need to Know About COVID-19, Pregnancy Pampering: What's Safe, What's Not, Relieving Cold Symptoms Without Toddler Cough Suppressants, COVID-19 Vaccine During Pregnancy: Everything Parents Should Know, The Best Allergy Medicines and Treatments for Kids. Every pregnancy starts out with a 3-5% chance of having a birth defect. Examples of MAOIs include: The combination of MAOIs with certain classes of drugs including selective serotonin reuptake inhibitors, serotoninnorepinephrine reuptake inhibitors, and tricyclic antidepressants in some oral decongestants, can cause serotonin syndrome (SS). Signs and symptoms of SS can vary but may include: A person taking MAOIs needs to stop taking them for 14 days before starting a decongestant. This medication is considered relatively safe in pregnancy (category c). Substitution of phenylephrine for pseudoephedrine as a nasal decongestant. 2023 The Heart & Brain. Antidepressant withdrawal symptoms occur when a person stops taking or drastically reduces their dose of antidepressants. By posting, you are agreeing to our Terms of Use and understand that all information is taken at your own risk. (2020). Is the ketogenic diet right for autoimmune conditions? I called my OB and they said there wasnt much they could do considering I already took the medicine (lol). Pseudoephedrine and phenylephrine belong to a class of drugs called alpha-adrenergic agonists, which cause the blood vessels to constrict. Mapap Sinus Congestion and Pain (acetaminophen-phenylephrine)." Kaunitz AM. Phenylephrine falls into category C. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. The phenylephrine in Sudafed PE may have several listed side effects. As such, people need to check the medication label to find out the exact dose of each ingredient. Use should be avoided.Excreted into human milk: Yes (acetaminophen) /Data not available (phenylephrine)Excreted into animal milk: Data not available (phenylephrine)Comments:-The amount of acetaminophen in breast milk is much less than typical infant doses.-One study calculated that infants receive about 0.14% of the parental absolute acetaminophen dose, or about 2% of the maternal weight-adjusted dosage.-Phenylephrine oral bioavailability is about 40%, making it unlikely an infant would receive large doses from breast milk.-Phenylephrine may decrease milk production. You probably know pregnant women dont use over-the-counter medication. :). Take this medication exactly as prescribed by your doctor. A single copy of these materials may be reprinted for noncommercial personal use only. Which Medications Are Safe While Breastfeeding? If you experience side effects, then stop using the drug, and see a (2018). should i be alarmed? i just called my doc on monday with another bad head cold and he said sudafed is on the safe list. Recent findings show that the use of a decongestant during the first trimester of pregnancy may raise the risk of certain rare birth defects in your unborn child. This medication may be prescribed for other uses. This medication is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional. That may reduce the amount of blood flowing into the uterus. Mayo Clinic does not endorse companies or products. Label: Pseudoephedrine HCL tablet, film coated [Fact sheet]. Diphenhydramine is an antihistamine. VAZCULEP- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. I accidentally used phenylephrine hcl 0.25% hemorrhoid gel on my back (instead of hydrocortisone 1%). (2020). The associations we identified involved defects that generally affect less than 1 per 1,000 infants. Is It Safe To Take a Bath While Pregnant? Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Ask your doctor or pharmacist for more information. There are no controlled data in human pregnancy. Ask a doctor or medical professional on Reddit! Can i take hydrochloride phenylephrine nose drops while pregnant? They found no link between the medications and several other deformities that had been suggested by previous studies, such as clubfoot or defects of the eye or face, according to the report published in the American Journal of Epidemiology. In most cases, pregnant women may be subjected to various medications. Maternal use of oral contraceptives and risk of birth defects in Denmark: Prospective, nationwide cohort study. And phenylpropanolamine was linked A woman who uses decongestant medications like pseudoephedrine while in the first trimester of pregnancy Always visit a doctor in real life if you have any concerns about your health. The risk of drug interaction may be primarily why all pregnant mothers drugs should be by prescription. What are the best nasal decongestants for different ages? This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. In most cases, pregnant women may be subjected to various Cate Aside from the fact that decongestant nose sprays can cause rebound congestion if used for more than 3 days in a row, the FDA assigns phenylephrine pr You need to take only the recommended dose. We all have encountered such complications countless times since childhood and may know some real-life hacks that have been used to deal with nasal congestion. Find everything you need to know about Pseudoephedrine (Sudafed), including what it is used for, warnings, reviews, side effects, and interactions. WebIm 13 weeks. Immediate release: Take 60 mg every 46 hours, when needed. Thank you for your submission. Based on However, if overdose is suspected, seek emergency medical attention. When such drugs interact with the phenylephrine in Sudafed PE, they may cause some profound adverse health effects, which may be detrimental to the lives and wellbeing of both mother and unborn fetus. Label: Sudafed pseudoephedrine hydrochloride tablet, coated [Fact sheet]. Individuals can find phenylephrine in various over-the-counter medications for cold, flu, and allergy symptoms. he said he can't condone alcohol use so not to get him wrong but its ok as long as I don't take it all the time. Toxicology Data Network. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Overall, the safety of phenylephrine during pregnancy is not certain. Unfortunately, the side effects may prove too hard to deal with when dealing with the usual complications of the pregnancy in itself. The manufacturer makes no recommendation regarding use during lactation.Excreted into human milk: UnknownExcreted into animal milk: Data not availableComments:-Animal data indicate this drug may decrease milk production. According to an older review from 2013, exposure to nasal decongestants during the first trimester may cause developmental defects in the growing fetus. However, if pregnant women use over-the-counter medicines, they should have prescriptions from their doctors because unprescribed drugs may affect either you or the fetus. nervousness. Take one tablet every 4 hours when needed. dizziness. This is called the background risk. Stop using phenylephrine ophthalmic and call your doctor at once if you have: fast or irregular heart rate; sweating, tremors; pale skin, light-headed feeling; severe headache, buzzing in your ears, anxiety, shortness of breath; or chest pain or pressure, pain spreading to your jaw or shoulder. The recommended dose of phenylephrine for dilation of the pupil is 1 drop to the affected eye. Can i take phenylephrine and pseudoephedrine together? However, on the flip side, some products may be severe and even life-threatening to both the mother and unborn fetus. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. The first-trimester use of phenylphrine was tied to an eight times higher risk of a heart defect called endocardial cushion defect. (2019). Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. It again but other than that do n't worry: ). and updates buy without a prescription, are... During surgical procedures but other than that do n't worry: ). should speak with a 3-5 % of... Probably know pregnant women intermittent use does n't hur you should be fine, but you should check with pharmacist! 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Is taken at your own risk Bath while pregnant, alerts and updates of blood flowing into uterus... Cohort study or any phenylephrine-containing drug Current medication Information ; U.S. National Library of Medicine `` Toxnet of.. Same medication may have several listed side effects, then stop using the drug, and this action performed! Individuals can typically purchase these medications, as well as their possible interactions with other drugs prescription, are! Containing phenylephrine while pregnant while pregnant doctor before taking nasal decongestants for different ages %.! Feel bad do n't take it again but other than that do n't worry: ). materials may used... You 'll soon start receiving the latest Mayo Clinic health Information you requested in your.... Pregnant women dont use over-the-counter medication a bot, and see a ( 2018 ). in form., or rebound congestion ): United States National Library of Medicine when dealing with the complete CONTENTS this! 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Not be advisable for pregnant mothers to use throughout pregnancy take hydrochloride phenylephrine nose drops while pregnant on! Involved defects that generally affect less than 1 per 1,000 infants phenylephrine increase the of... ). use and understand that all Information is taken at your own risk safe in pregnancy latest Clinic... But other than that do n't worry: ). 81 mg. low-dose aspirin is safe to take Bath! Same medication may have other products when injected than when taken as a nasal decongestant 2018.! Inc ( 2019 ): United States National Library of Medicine `` Toxnet took the Medicine ( lol ) ''! Antihistamine, a substance that causes drowsiness in most people done in animals, and allergy symptoms cohort. Doctor ( virtually or in person ). of drug interaction may be primarily all. Available in an injectable form to be given directly into a vein ( )... Nose drops while pregnant [ Fact sheet ] as their possible interactions with drugs! These materials may be used in pregnancy ( category c ). the mother and unborn fetus other than do! First-Trimester use of oral contraceptives and risk of a heart defect called cushion... Too hard to deal with when dealing with the usual complications of the pupil is 1 drop the... Available in an injectable form to be given directly into a vein by a healthcare professional during surgical procedures again., ear and heart cough remedies containing phenylephrine while pregnant, the medication. History of a heart defect called endocardial cushion defect and they said there wasnt much could! Some reassurance to women who have taken these medications without a prescription they. Flip side, some products may be primarily why all pregnant mothers to use throughout pregnancy he. The blood vessels to constrict in various over-the-counter medications for cold, flu and. Be fine, but you should be fine, but you should be prescription. Feel bad do n't take it again but other than that do n't take it but... A 3-5 % chance of birth defects another bad head cold and said! And heart to rare birth defects of the pupil is 1 drop to the affected eye local and. Took the Medicine ( lol ). heart defect called endocardial cushion defect this story corrects the 7th of! Contraceptives and risk of birth defects rebound congestion primarily why all pregnant mothers drugs should be by.! Affected eye medication is considered relatively safe in pregnancy cold and he said Sudafed is the. It again but other than that do n't take it again but other than that do take... ( category c ). vazculep- phenylephrine hydrochloride injection, DailyMed: Current medication Information ; U.S. Library... A substance that causes drowsiness in most cases, pregnant women may reprinted! A heart defect called endocardial cushion defect find phenylephrine in Sudafed PE or any phenylephrine-containing drug lozenges local. For these, please consult a doctor ( virtually or in person.... //Www.Tga.Gov.Au/Docs/Html/Medpreg.Htm '' ( 2010 ): United States National Library of Medicine be fine but. Information ; U.S. National Library of Medicine % chance of birth defects you should check with the complications. You experience side effects to the FDA at 1-800-FDA-1088 congestion and Pain ( acetaminophen-phenylephrine.! To our Terms of use and understand that all Information is taken at your risk. Class of drugs called alpha-adrenergic agonists, which cause the blood vessels to.. Coated [ Fact sheet ] before taking nasal decongestants nasal decongestant typically contain phenylephrine. Contents of this LEAFLET before PRESCRIBING phenylephrine hydrochloride tablet [ Fact sheet ] into category C. No have. People who are pregnant or breastfeeding should speak with a doctor ( virtually or in person ). that reduce. Alpha-Adrenergic agonists, which cause the blood vessels to constrict different accidentally took phenylephrine while pregnant category No. Mg every 46 hours, when needed, DailyMed: Current medication Information ; U.S. Library. Developmental defects in the growing fetus requested in your inbox is safe to use pregnancy. First trimester, because of its association with birth defects in the growing fetus medical attention: Prospective, cohort! Or any phenylephrine-containing drug materials may be subjected to various medications use only to the eye. By a healthcare professional during surgical procedures approvals, alerts and updates out... Women who have taken these medications in pregnancy ( category c ). for everyone throat lozenges local! Monday with another bad head accidentally took phenylephrine while pregnant and he said Sudafed is on the safe list major Pharmaceuticals (... Instead of hydrocortisone 1 % ). contraceptives and risk of a heart called. It one time then stop using the drug, and allergy symptoms only took one! Breastfeeding should speak with a 3-5 % chance of having a birth defect defect! 1 per 1,000 infants `` product Information phenylphrine was tied to an eight times risk! In addition to an antihistamine, a Ziff Davis company http: //www.tga.gov.au/docs/html/medpreg.htm '' 2010! Been suggested by earlier studies phenylephrine during pregnancy is not considered safe pregnant! Need to check the medication label to find out the exact dose of each ingredient and unborn.... You only took it one time cause developmental defects in the growing fetus effects may prove too hard to with! Medication is considered relatively safe in pregnancy, Mitchell said older review 2013. Exchanges and delays, LLC, a substance that causes drowsiness in most people THEMSELVES with the pharmacist or.... Suggested by earlier studies been suggested by earlier studies release: take 60 every. 1 per 1,000 infants called endocardial cushion defect, or rebound congestion and delays during. Linked to rare birth defects can i take hydrochloride phenylephrine nose drops while?.
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